Asymmetric dimethyl-arginine (ADMA) response to inflammation in acute infections
نویسندگان
چکیده
منابع مشابه
Asymmetric dimethyl-arginine (ADMA) response to inflammation in acute infections.
BACKGROUND AND METHODS The endogenous inhibitor of nitric oxide synthase (NOs) asymmetrical dimethyl-arginine (ADMA) has been implicated as a possible modulator of inducible NOs during acute inflammation. We examined the evolution in the plasma concentration of ADMA measured at the clinical outset of acute inflammation and after its resolution in a series of 17 patients with acute bacterial inf...
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Asymmetric dimethyl arginine [ADMA] is a nitric oxide synthase inhibitor and reduces nitric oxide [NO] generation. It is considered an important cardiovascular risk marker. It is raised in various clinical conditions like hypertension, ischemic heart disease, cardiac failure, diabetes mellitus, obesity and toxaemia of pregnancy. Certain drugs used to treat these conditions have additional ADMA ...
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OBJECTIVE Endothelial dysfunction by the loss of nitric oxide (NO) is a critical event during reperfusion of ischemic myocardium. Reduced NO availability signals important pathophysiological changes leading to myocardial reperfusion injury. We have recently shown that NO biosynthesis can be disturbed by the endogenous NO synthase (NOS) inhibitor ADMA and that these changes are mediated by an im...
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Obesity is associated with the development of various metabolic diseases. Adipose tissue-derived factors may underlie this relationship. Two novel adipose signals associated with increased risk of coronary heart disease were investigated; interleukin-6 (IL-6) and the endogenous nitric oxide inhibitor, asymmetric dimethyl arginine (ADMA). The effect of the cyclo-oxygenase (COX) pathway on basal ...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2007
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gfl719